Maturing is not an illness. It is an all-natural process that impacts all living microorganisms. Yet it is likewise the primary danger factor for several chronic conditions that hinder health and wellness. What happens if we could slow down or even turn around the aging process, and extend our healthspan, the duration of life devoid of chronic conditions and functional decrease?
This is not a dream, but a subject of significant research and financial investment. Scientists have determined 12 main “hallmarks of ageing” that are coming to be significantly well-understood. These include DNA damage, mobile senescence, stem-cell fatigue, and swelling. These hallmarks are not independent entities, yet instead make up a complicated network of mutual interactions.
The best goal of geroscience is to discover means to intervene in this network and target the characteristics of aging. Several of the prospective treatments are calorie limitation, medications, gene therapy, and stem-cell therapy. For example, calorie limitation has been shown to prolong lifespan and healthspan in numerous animal designs by modulating several hallmarks of ageing. Drugs such as rapamycin and metformin have actually also been reported to have anti-ageing results by inhibiting pathways that promote mobile development and swelling. Gene therapy could potentially correct or customize genetics that are involved in aging …